If so, this article will provide information that will help you determine if the supplement is right for your hair growth goals. The chemical formula for methylsulfonylmethane is CH 3 2 SO 2. The compound occurs naturally and is found in a variety of foods, such as green vegetables, garlic, seafood, onions, and milk.
Many women take MSM for hair growth because the chemical compound contains sulfur, which is one of the primary building blocks for your hair. But, will methylsulfonylmethane actually make your hair grow? Some medical professionals suggest that methylsulfonylmethane can be used as a supplement for increasing hair growth.
It is also believed by many people that MSM can increase the rate of hair growth since it elongates the anagen phase of the hair growth cycle. The anagen phase of the hair growth cycle is commonly referred to as the growth phase.
If the supplement can significantly increase the rate of hair growth, this would be a scientific breakthrough. Some were recalled, like Hismanal.
I took valsartan for several years before learning it contained a carcinogen. Patients are at a disadvantage, and medicine is more and more run as a business, interested only in the bottom line. A: We are so sorry to hear that you have been ill. The liver doctor is no doubt aware that a few herbal supplements, such as kava extract, black cohosh, green tea extract and germander, can be harmful to the liver Food and Chemical Toxicology, September On the other hand, as you point out, there are hundreds of drugs that can cause liver injury Expert of Gastroenterology and Hepatology, January We encourage you to monitor your liver function periodically to make sure the abnormal test results were an anomaly.
Is this amount OK? We think that is low, but your intake of 10, IU is very high. According to the experts, the upper limit should be 4, IU a day. You can read more about this topic in our Guide to vitamin D Deficiency. MSM supplementation provided statistically significant improvements in the condition of the hair and nails as determined by expert grading and subject self-assessment.
MSM appears to benefit hair and nail health, possibly by its action on keratin, which is a major building-block for the hair and nails. It is synthesized by keratinocytes and is insoluble in water, which helps to protect the hair and contributes to its impermeability.
The hair contains 18 amino acids, including proline, threonine, leucine, and arginine. Keratin is particularly rich in cysteine. Cysteine is a sulfurated amino acid that forms disulfide bonds between molecules and thus lends the structure strength and resistance. Aging and excessive exposure of hair to solar irradiation cause dryness, reduced strength, a rough surface texture, loss of color, decreased luster, stiffness, brittleness, and an overall dull, unhealthy appearance.
Nails are composed of a protective protein called alpha-keratin, which imparts tough rigidity. Nails get their strength from 3 linked keratin layers, where oils and moisture cement and lubricate the nail plate. Functionality results from the nail shape, which mirrors that of the underlying bone.
Hair and nails that maintain tight inter-corneocyte connections are generally not subject to desquamation. However, hair is shed through life-cycle programming, and nail corneocytes are eroded due to friction and physical activity. The effect of the diet on aging skin has gained increasing attention over the past few decades 6 and studies on the effects of dietary supplements have confirmed that such supplementation can help to maintain and even improve skin, hair, and nail condition.
In , Jacquet et al 7 reported that a dietary supplement containing mg shark cartilage, 1. Other studies have demonstrated that the oral intake of minerals like zinc zinc monohydrate , B vitamins, 10,12,13 and L-cystine 10 has beneficial effects on hair and nails, and 5-alpha-reductase inhibitors are useful for addressing hair loss. Methylsulfonylmethane MSM is naturally present in the environment. It is found in plants as well as the milk of both bovines and humans and may provide a source of sulfur for the essential amino acid methionine.
MSM has been reported to affect the compartmentalization and metabolism of sulfur. MSM may donate sulfur to keratin, which could help strengthen the bonds between keratin molecules in the hair and nails. When administered orally, MSM is rapidly absorbed, well-distributed, and efficiently excreted from the body.
It is well-tolerated by most individuals at dosages of up to 4 g daily, with few known and mild side effects. Therefore, a prospective clinical study was designed to examine the effect of oral administration of MSM on the condition of the hair and nails. In addition, this study sought to identify the best dose for optimum efficacy. The study was conducted at a third-party clinical testing facility International Research Services Inc.
The study was approved by the Allendale Institutional Review Board IRB , and informed consent was obtained from each participant prior to enrollment. A total of 63 subjects completed the study. They were healthy with no acute or chronic disease or medical condition, including dermatological problems, that could put them at risk in the opinion of the Principal Investigator or compromise study outcomes.
Subjects who regularly used nutritional supplementation within the previous 2 weeks were excluded. The subjects were not participating in any other clinical studies involving the face. Pregnant and lactating women were excluded. The regular use of facial products and color-cosmetics for at least 2 weeks prior to study enrollment was allowed during the study period.
In contrast, the use of other systemic or topical medications and treatments was prohibited during the study. The panel was divided into 2 groups. The subjects were instructed to take the capsules in the morning with or without food for 4 months and to refrain from using any hair or nail treatment products and from receiving manicures for the course of the study.
Expert visual grading of hair shine, volume, overall health and split ends was conducted at baseline and at weeks 4, 8, 12, and This grading scale was created and validated internally by IRSI and used a cm scale where 1 was none and 10 was extreme for each parameter.
At each time point, the subjects also assessed the same parameters via a questionnaire that asked the participants to indicate their level of agreement with a statement regarding the results on a 5-point scale.
Nails were also visually graded by trained experts using a cm scale, where 1 was none and 10 was extreme for nail shine and overall appearance at baseline and at weeks 2, 4, and 8.
At each time point, the subjects also assessed the condition of their nails via a questionnaire. Visual assessments were analyzed with descriptive statistics; paired t-test monadic.
Figure 1 shows the effects of oral administration of MSM on hair condition. With respect to the visual grading of hair condition Fig. In the subject self-assessment of hair condition Fig. Only 1 of the subjects in Group A disagreed after 4 weeks and 16 weeks. Only 2 of the subjects in Group B disagreed after 4 weeks and 16 weeks. While visual grading of split ends did not show a change with treatment, most subjects noticed some improvement with use Fig. In Group A, only 4 subjects disagreed after 4 weeks and 1 disagreed after 16 weeks.
In Group B, 4 subjects disagreed after 4 weeks and 2 disagreed after 16 weeks. Most subjects agreed that the product improved their hair volume Fig. As shown in Fig. As with the other parameters, most of the subjects agreed that treatment resulted in an overall healthier appearance Fig.
Figure 1. Figure 2 shows assessments of nail condition after treatment with MSM. As observed in Fig.
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